Neurotoxic Syndrome Developed after Taking Sertraline and Risperidone

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Neurotoxic Syndrome Developed after Taking Sertraline and Risperidone

Neuroleptic malignant syndrome and serotonin syndrome share many common clinical features, and the term "Neurotoxic syndrome" can be used when a clear distinction cannot be made between the two. Here we present a case of 19-year-old man who experienced serotonin syndrome caused by sertraline intake, and consecutive neuroleptic malignant syndrome by risperidone. This case suggests that these two...

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Stevens-Johnson syndrome after sertraline.

Sir, Sertraline (Zoloft1) is a new selective inhibitor of serotonin re-uptake. This family of antidepressant drugs is considered to be safe, and cutaneous adverse reactions have rarely been reported (1). We report here a patient who developed StevensJohnson syndrome (SJS) after starting treatment with sertraline (Zoloft1). A 96-year-old woman was admitted with a cutaneous and mucosal eruption. ...

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Addition of risperidone to sertraline improves sertraline-resistant refractory depression without influencing plasma concentrations of sertraline and desmethylsertraline.

In the present study, we examined the efficacy of risperidone addition on sertraline-resistant depressed patients and the effects of risperidone on the metabolism of sertraline. Ten patients (M/F: 4/6, age: 54 +/- 10 years) met the DSM-IV criteria for major depressive disorder enrolled the study. Hamilton Dating Scale for Depression (HAM-D) scores (mean +/- SD) in all 10 patients significantly ...

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Spontaneous seizures after ECT in a patient medicated with bupropion, sertraline and risperidone.

Objective: To report a case of post-electroconvulsive therapy spontaneous seizures in a patient medicated with sertraline, bupropion and risperidone. Case description: A 53-year-old woman with recurrent major depression was admitted to our psychiatry department for a major depressive episode of 6 weeks' duration, with psychotic symptoms. She was already on 200 mg/day of sertraline and 2 mg/da...

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Cyclic Vomiting Syndrome Developed after Stroke

Cyclic vomiting syndrome is characterized by recurrent episodes of stereotyped vomiting separated by regular symptom-free periods. We describe a case of cyclic vomiting syndrome developed after stroke, which has not been reported to date. A 69-year-old woman experienced recurrent vomiting following left cerebral infarct. The patient's vomiting pattern was consistent with cyclic vomiting syndrom...

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ژورنال

عنوان ژورنال: Journal of Clinical Neurology

سال: 2007

ISSN: 1738-6586

DOI: 10.3988/jcn.2007.3.3.165